Consultant — Rare Diseases Lead
Position: Consultant — Rare Diseases Lead
Tel: +44 (0) 1223 913 025
As the Rare Diseases Lead at Costello Medical, Annabel leads a range of project types across our different service offerings, and has a specialist interest in orphan and ultra-orphan indications.
Annabel has experience in a wide-range of rare diseases, including paediatric conditions and genetic disorders, where she has led teams to successfully provide high-quality project support at various stages of clinical development. Annabel is passionate about the societal value of treatments for rare diseases and is dedicated to the delivery of pro bono support to a number of rare disease charities, including our long-term collaboration with the rare disease charity Findacure. Annabel plays an active role in academic discussions in this area, leading an issue panel at the 2016 European ISPOR conference focussed on off-label treatments in rare diseases. Annabel was also a panellist at DPharm Europe 2016, discussing Costello Medical’s ongoing collaborative work developing economic models focused on drug repurposing in rare diseases.
Prior to joining Costello Medical in April 2015, Annabel completed a PhD in Cell and Developmental Biology at the University of Cambridge, having previously received an upper second class BA in Natural Sciences at the same institution. During her PhD, Annabel used a combination of imaging, genetics and computer modelling to examine the role and relationship of four intracellular proteins that mediate the link between cells and the surrounding extracellular matrix. Following her PhD, Annabel volunteered with a non-governmental organisation in Cambodia, cementing her enthusiasm for the healthcare sector and charity work.
Tel: +44 (0) 1223 913 075
Since joining Costello Medical in the middle of 2015, Matt has gained experience in a number of disease areas, including rheumatology and haemophilia. He has worked on a variety of medical affairs and market access projects, such as medical education materials and events, and has provided scientific support for satellite symposia.
Matt graduated from the University of Cambridge in 2011 with a first class BA in Natural Sciences, specialising in Biochemistry. During this time, he conducted research on sleeping sickness as a summer research fellow at the Rockefeller University, as well as investigating the role of collagen in blood clotting as part of his final year dissertation. In 2015, Matt completed his PhD at the MRC Laboratory of Molecular Biology in Cambridge, where his research focus was the molecular mechanism of bacterial cell division.
Matt particularly enjoys the scientific variety and client-oriented aspects of his role, and is excited to have the opportunity to continue to apply and develop his skills through undertaking a broad range of projects as part of the Costello Medical team.
Tel: +44 (0) 1223 913 074
Jenni graduated from the University of Warwick in 2011 with an upper second class honours degree in Biomedical Science. She then went on to study for a PhD in Biological Sciences with the same institution. Her research focused on the immunogenicity of the glycoprotein of rabies and the lyssaviruses, with the aim of developing a construct capable of pan-lyssavirus neutralisation.
She joined the company in April 2015 and has managed a wide range of different literature reviews; from targeted reviews in ophthalmological conditions to systematic literature reviews in oncology for the purpose of HTA submissions. In 2017 she also completed the Postgraduate Certificate in Health Economics for Health Care Professionals at the University of York.
Position: Senior Analyst
Tel: +44 (0) 1223 913 079
Bryony graduated from University College London with a first class honours degree in Natural Sciences, specialising in Neuroscience, Mathematics and Statistics. As an undergraduate she completed a summer internship at the John Innes Centre working on calcium flux detection in legumes. Through this internship Bryony developed a keen interest in biological modelling using her favourite programming language, R.
She then went on to complete a Masters degree in Computational Biology from the University of Cambridge. For her Masters thesis Bryony completed a joint project with AstraZeneca and Cancer Research UK. This project explored integrative clustering of genomic, mutation and copy number data as a way of determining novel non-small cell lung cancer subtypes which may have differing drug responses. After graduating Bryony worked as a financial analyst at the London Ambulance Service where she developed her knowledge of the public sector.
Bryony joined Costello Medical in February 2016. She is excited to develop her statistical and programming skills further whilst working on a wide variety of projects, and is looking forward to contributing to the growth and development of the company.
Position: Senior Analyst
Tel: +44 (0) 1223 792 479
Kate graduated from the University of East Anglia in July 2014 with an upper second class degree in Biochemistry. For her final year research project she investigated the roles DNases play in preventing the re-establishment of Campylobacter biofilm populations. The results generated from this project went on to be published in two peer-reviewed scientific journals. Following her undergraduate degree, Kate completed a Masters degree in Epidemiology at Imperial College London in 2015.
Motivated to work within the healthcare industry and improve the lives of patients, Kate joined Costello Medical as a Scientific Intern and was delighted to transition into the permanent role of Analyst in March 2016. Since joining Costello Medical, Kate has worked on a diverse range of projects across several disease areas in the Evidence Development and HTA and Health Economics Divisions. She has particularly enjoyed becoming involved with the company’s pro bono projects, which have focused on benefiting patients who suffer from rare diseases in the UK. Kate looks forward to working within the talented and dynamic team at Costello Medical as well as further developing and applying her scientific knowledge across a variety of projects.
Senior Health Economist
Position: Senior Health Economist
Tel: +65 69 20 80 14
Wrik graduated from the University of Oxford in 2014 with an upper second class honours degree in Economics and Management. Following this, he completed a Masters degree in Health Economics at the London School of Economics and Political Science. For his dissertation, Wrik worked on a placement at the Performance Insight Team of the Department of Health, investigating equitable maximum waiting time standards in England, through an analysis of QALYs forgone whilst waiting.
Wrik joined Costello Medical as a Health Economist in October 2015. He is looking forward to applying his knowledge and skills, in particular economic modelling, to a variety of projects, whilst further pursuing his interest in this field.
Senior Medical Writer
Position: Senior Medical Writer
Tel: +44 (0) 1223 792 536
Eleanor graduated in 2016 with a First Class Masters degree in Chemistry from Oxford University. As an undergraduate, she completed a summer internship working in a specialist oligonucleotide synthesis company. Through this experience, Eleanor developed a keen interest in biological sciences which led to a final year research project in Biochemistry. For her thesis, she investigated the effects of 2-oxoglutarate dependent oxygenases on the efficacy of antibiotics, and consequently discovered an interest in scientific writing.
Motivated by her desire to support future pharmaceutical innovation, Eleanor joined Costello Medical as a Medical Writer in September 2016. She is keen to produce high quality documents and presentations to communicate effectively the exciting new advancements of clients. Eleanor is also eager to expand her current knowledge of the healthcare system and is looking forward to working on a wide variety of projects.
Position: Medical Writer
Tel: +44 (0) 1223 792 491
Aimée graduated in 2012 from Durham University with a Masters degree in Physics. For her Masters project and as an astrophysics PhD student at the University of Cambridge, her research focused on image analysis and building a data reduction pipeline to detect small changes in starlight that hint at the presence of planets outside of our solar system. She presented her research at national and international conferences and also enjoyed coordinating the department’s graduate outreach programme for communicating with the public.
Aimée decided to leave academia and transition to a healthcare career as she wanted to make a wider contribution to society and use her scientific experience to improve people’s lives. She completed a Scientific Internship at Costello Medical at the end of 2016 and experienced regular cross-divisional work across many areas of the company. She is very excited to apply her analytical skills and statistical knowledge to a wide variety of projects, including publication development, biostatistics research and pro bono projects.