HTA and Health Economics
Position: Scientific Director
Tel: +44 (0) 1223 913 040
As Scientific Director of Costello Medical, Jeanette oversees the running of all the scientific teams, ensuring that they are delivering top quality work and customer service to our clients. Throughout her 8 years at the company, Jeanette has worked across the full range of service offerings, giving her a valuable insight into the different challenges experienced by each team and allowing her to provide essential guidance to scientific team members across all areas. Jeanette’s role additionally encompasses overseeing the business development activities of Costello Medical and she took on the role of Head of the London Office when this opened in January 2017.
Jeanette founded the Health Technology Assessment and Health Economics division in January 2013 and built this team up from scratch to be one of the leading HTA providers in the UK, before she transitioned into the Scientific Director role in April 2016. She chose to specialise in health economics for some years as she believes that the evidence based decision making process for healthcare funding decisions that a health economic framework allows is essential. She continues to employ her specialist knowledge directly on projects in an advisory capacity.
Jeanette believes that the opportunity provided by Costello Medical to work within a dynamic, productive team at the forefront of their field is second to none. She enjoys getting involved in all aspects of the company and has particularly enjoyed mentoring the personal development of many talented individuals over the last few years.
Jeanette originally graduated from the University of Cambridge in 2009, achieving a first class honours BA and upper second class honours MSci in Natural Sciences, specialising in Biochemistry. She more recently graduated with a Masters in Health Economics from the University of York, achieving a distinction.
Head of HTA and Health Economics
Position: Head of HTA and Health Economics
Tel: +44 (0) 1223 913 032
In his role as Head of HTA and Health Economics, Matt is responsible for the delivery of client projects in the field of Health Technology Assessment. Matt has experience in managing a variety of project types, including HTA submissions, health economic manuscripts and systematic reviews, and he relishes the technical and strategic challenges posed by these projects. In addition, Matt enjoys his responsibilities in training, recruitment and business development for the HTA Team.
Matt brings to the role an avid interest in the healthcare industry, as well as an ambition to constantly further his personal development, for instance by pursuing a distance learning Master’s degree in Health Economics at the University of York in 2015-2016. Prior to joining Costello Medical, Matt graduated with upper second class honours in Natural Sciences from the University of Cambridge, specialising in immunology and microbiology.
Matt is delighted to be surrounded by such an enthusiastic team at Costello Medical, and is looking forward to playing a key role in the further development of Costello Medical’s HTA and Health Economics Division.
Tel: +44 (0) 1223 913 021
As a Consultant in the HTA and Health Economics Division, Rose has led a variety of HTA and health economics projects across multiple disease areas, including NICE and SMC submissions, health economic manuscripts and systematic literature reviews. In order to further her expertise in this area, Rose is currently studying towards a Postgraduate Diploma in Health Economics from the University of York.
Rose holds a first class Masters degree in Pharmacy from the University of Nottingham. After completing her pharmacist training year at University College Hospital in London in 2013, Rose spent two years working as a hospital pharmacist at Changi General Hospital in Singapore. Here she gained experience in a variety of clinical specialties and completed a Postgraduate Certificate in Clinical Pharmacy by distance learning from Queen’s University Belfast.
Consultant Health Economist
Position: Consultant Health Economist
Tel: +44 (0) 1223 792 475
As a Consultant Health Economist at Costello Medical, Natalie has experience in the development, critique and adaptation of health economic models spanning simple, Markov and DES models. She has managed and been the lead Health Economist on several modelling projects across a range of therapeutic areas from rare to common diseases, including chronic and infectious conditions, and medical devices. Natalie especially enjoys the technical challenges of her work, and applying her mathematical background within the medical sector.
Natalie graduated from the University of Oxford in 2010 with a first class Masters degree in Mathematics. She then went on to complete a DPhil in Applied Mathematics through the Systems Biology Doctoral Training Centre at the same university. Her doctoral research focused on modelling the fluid flow, chemical concentration and cell growth within hollow fibre membrane bioreactors, with applications to tissue engineering. This involved close collaboration with experimentalists working in the field of regenerative medicine. Since graduating, Natalie has gained further research and modelling experience through working in technology consultancy across a variety of industries, including within the medical sector.
Tel: +44 (0) 1223 913 044
Peter graduated from the University of Oxford in 2013 with an upper second class honours degree in Biochemistry. In his final year research project he investigated the role of chromatin-binding proteins in transcriptional control, with a particular focus on oncogene activation. As an undergraduate, Peter also obtained research experience working in the genetics department at AstraZeneca as part of two summer placements. Peter has since developed his interest in healthcare and translational research further via an internship at Cancer Research UK, which focused on the charity’s expansion into the development of biologics for cancer therapy.
In September 2015, Peter was delighted to join the Costello Medical team as an HTA Analyst following an internship with the company. In particular, he looks forward to supporting clients with their submissions to UK HTA bodies, and to working across a variety of therapeutic areas.
Position: Project Consultant
Tel: +44 (0) 1223 913 066
Stephen is responsible for the delivery of client projects in the field of Health Technology Assessment and health economics and is particularly interested in the technical and strategic challenges posed by these projects. Since joining the company, Stephen has managed a variety of project types including HTA submissions (NICE, SMC, AWMSG and NCPE), health economic manuscripts and related systematic reviews and has co-authored a variety of related manuscripts in the peer-reviewed literature. He has also led the development of cost-minimisation and budget impact models and provided strategic advice on the technical development of Markov and discrete event simulation cost-effectiveness models; additionally, he has presented his original research as an oral presentation at the ISPOR Congress.
Stephen joined Costello Medical in April 2014, having spent several years publishing peer-reviewed scientific and medical journals for Wiley, and previously for the Royal Society of Chemistry. He enjoys drawing on his experience in pharmacy, research and publishing to help clients communicate the economic and clinical value of their products effectively. He is particularly pleased to be part of such an experienced and enthusiastic team delivering scientific excellence in a thriving commercial environment, and to be able to contribute personally to Costello Medical’s continued growth and success.
Originally, Stephen graduated with a first class honours Master of Pharmacy degree from the Queen’s University of Belfast in 2005. Following successful completion of his qualifying year he registered as a pharmacist and returned to Queen’s to undertake research on the pharmacokinetics of certain drugs in use in neonates, combining dried blood spot microsampling methods and population pharmacokinetic modelling techniques, leading to the award of a Doctor of Philosophy degree in 2010. He is a full member of both the Royal Pharmaceutical Society and the Royal Society of Chemistry.
Senior Health Economist
Position: Senior Health Economist
Tel: +44 (0) 1223 792 542
Gengshi leads and contributes to HTA submissions, health economic models, health economic manuscripts, and literature reviews for pharmaceutical and medical device clients. Gengshi is particularly interested in the challenges associated with the economic evaluation of diagnostic technologies and enjoys contributing to model conceptualisation and to implementation of decision tree and Markov models.
Between 2014 and 2016, Gengshi worked in Costello Medical’s Singapore office to support the Head of Asia-Pacific in establishing the regional client base and in growing the Costello Medical Asia-Pacific team.
Gengshi graduated from the University of Cambridge in 2013, achieving a first class honours BA and upper second class honours MSci, specialising in Biochemistry. Taking the opportunity to pursue further studies via distance learning whilst working at Costello Medical, Gengshi graduated in 2017 with a Masters in Health Economics from the University of York.
Senior Health Economist
Position: Senior Health Economist
Tel: +65 69 20 80 14
Since joining Costello Medical as a Health Economist in October 2015, Wrik has led the de novo development of cost-effectiveness models, burden of disease models, and budget impact models, across a range of disease areas and interventions, including rare diseases and medical device projects. Wrik has been involved in several submissions to HTA bodies in the UK, including NICE and the SMC.
Wrik joined the Costello Medical Singapore office in October 2017, and has supported ACE submissions in Singapore at all stages of the process. This has involved building new economic models, the adaptation of models to local settings, and the writing of submission documents, as well as regular collaboration with clinicians. He is looking forward to expanding the health economic service offerings in the Asia-Pacific region and applying his knowledge and skills to a variety of projects.
Wrik graduated from the University of Oxford in 2014 with an upper second class honours degree in Economics and Management. Following this, he completed a Master’s degree in Health Economics at the London School of Economics and Political Science. For his dissertation, Wrik worked on a placement at the Performance Insight Team of the Department of Health, investigating equitable maximum waiting time standards in England, through an analysis of QALYs forgone whilst waiting.
Position: Senior Analyst
Tel: +44 (0) 1223 792 537
Since joining Costello Medical in September 2016, Katie has worked on a number of different project types with the HTA Division, including NICE and SMC submissions, as well as health economic manuscripts and briefing books. She has experience in a wide range of disease areas, including oncology, rheumatology and neurology. Katie has particularly enjoyed working on a variety of project types, as well as being involved in several internal initiatives. She is also excited about the opportunity to further her knowledge of health economics via distance learning at the University of York. Prior to joining Costello Medical, Katie completed a manufacturing excellence graduate scheme at a large FMCG company, focusing on problem solving and operations within a manufacturing environment, which included managing a large team and leading SixSigma projects.
Katie has an upper second class honours degree in Biological Sciences from the University of Liverpool. In her final year research project, she investigated whether different strains of Staphylococcus aureus were resistant to D-sphingosine found in the skin. She first became interested in healthcare and science through work experience placements at different NHS hospitals.
Position: Health Economist
Tel: +44 (0) 207 544 8521
Chris holds a BSc and MSc in Economics from the University of Manchester and completed his dissertation at the Manchester Centre for Health Economics, which has provided him with a good understanding of economics and statistics and their applications to healthcare. At Costello Medical, Chris has worked on a variety of models, such as Markov cost-effectiveness models and budget impact models, at all stages of the development process. In addition, he has provided modelling support for HTA submissions. Chris has experience with Stata and performing statistical analysis with large data sets.
Chris joined Costello Medical as a Health Economist Intern, before transitioning into the permanent role of Health Economist in July 2017. Chris has really enjoyed being involved with the company’s pro bono projects, and is looking forward to further developing his economic modelling skills.
Tel: +44 (0) 207 544 8524
Elizabeth graduated from the University of Oxford with a degree in Cell and Systems Biology in 2016. During her degree, she carried out a research project investigating the effects of monoamine oxidase inhibitors on circadian rhythms in cell culture. Prior to joining Costello Medical, she carried out an internship at Cancer Research UK (CRUK) in the Research Training and Fellowships Team. Whilst at CRUK, she analysed data surrounding successful applications for research fellowships and interviewed recipients of CRUK grants to assess their views on the research landscape.
Elizabeth joined Costello Medical as a Scientific Intern in April 2017, before transitioning to the Analyst role in August 2017. At Costello Medical, Elizabeth has enjoyed working on a variety of HTA submissions and on projects across a variety of divisions.
Tel: +44 (0) 207 268 3165
Molly graduated in July 2017 with a first class degree in Cells and Systems Biology from the University of Oxford. During her second year at university she completed a project investigating the ways in which different frequency sounds are represented in the primary auditory cortex of ferrets using two-photon imaging. This was amongst the first attempts to use this species for the technique in question, worldwide.
After really enjoying her Scientific Internship in the summer of 2016, Molly is excited to see the friendly faces at Costello Medical again after starting as an Analyst in September 2017. As part of the HTA Division, but also working cross-divisionally, she looks forward to the varied and interesting work with many different clients and colleagues.
Tel: +44 (0) 207 268 3168
Alex graduated from the University of Cambridge with a first-class degree in Natural Sciences in June 2017, specialising in Biochemistry in his final year. During his degree, he carried out an 8-week research project, investigating the essential mechanisms surrounding a variety of genetic diseases via a novel synthetic viability screening method and developing a UNIX command-line based pipeline to analyse the screening results.
Alex joined Costello Medical as a Cross-Divisional Analyst in September 2017. He has always had a keen interest in healthcare, so he is looking forward to applying his scientific knowledge across a wide range of projects and to develop new skills in the process. He is particularly excited to work on HTA submissions within his home division.
Tel: +44 (0) 207 268 3196
Patsy graduated with a first class BSc honours degree in Biochemistry at the University of Birmingham in 2013. During her undergraduate degree, Patsy spent one year working within the pharmaceutical industry as a research scientist focusing on drug discovery. In 2014, Patsy completed a Masters degree in Cardiovascular and Metabolic Diseases at the Institute of Metabolic Science in Cambridge where she subsequently completed her PhD in Clinical Biochemistry in 2017. Patsy had a strong interest in combining clinical and scientific research and during her doctoral training she investigated the molecular mechanisms of rare genetic disorders associated with the protein Phosphoinositide 3-Kinase. She has also presented her research at national and international conferences.
Patsy joined Costello Medical as a Cross-Divisional Analyst in January 2018 and is looking forward to expanding her knowledge of different disease areas and contributing to the improvement of medical healthcare through her work at Costello Medical.
Position: Health Economist
Tel: +44 (0) 1223 913 020
Scott graduated from the University of St Andrews with a first-class honours degree in Economics. During Scott’s undergraduate degree he became fascinated by the interplay between economics and the health sector, where he was exposed to game-theoretical Markov models as well as theoretical models of obesity. Scott’s undergraduate research dissertation, titled “Inequality in China – An Invisible Great Wall?”, involved synthesising Chinese economic data since 1978, and using a wide range of econometric modelling techniques to evaluate the relationship between China’s 1978 Economic Reforms and inequalities across income and health.
Scott joined the Costello Medical team as a Health Economist in April 2018 and is excited to grow his health economic modelling skills across a wide range of projects within a commercial setting.
Position: Project Assistant
Tel: +44 (0) 207 268 3988
Farzana completed her MSc at University College London in Cancer, for which she received an overall Distinction award. Her research project involved identifying changes in chromatin state induced by ETV6-RUNX1 in childhood ALL. This was carried out within the Bill Lyons Informatics Centre, where she worked on using ChIP-seq data to generate a segmentation pattern of chromatin states implementing a software called ChromHMM.
Prior to this she completed a BSc in Biomedical Science from Brunel University, where she achieved a first-class honours degree. Her final year project was laboratory based and entailed looking at the viability of Escherichia coli cells with rnhA and recJ mutation. Having gained some laboratory experience between her undergraduate and postgraduate studies, she was keen to learn more about the regulatory aspect of drug development, an interest which was piqued during her MSc course.
Farzana joined Costello Medical in February 2018 as a Project Assistant in the HTA and Health Economics Division. Interested in bridging the gap between science and business, she looks forward to applying her scientific knowledge and organisational skills across a wide range of projects.