Publications

At Costello Medical we offer a comprehensive publications service from project conception and initiation to submission and publication. Our Publications Team has a broad range of experience across cardiovascular pharmacology, musculoskeletal disorders, mental illness, neuroscience, oncology, biochemistry, medicinal chemistry and immunology. We believe that our clients value our personal and tailored approach, as well as our commitment to ensuring that the final publication is exactly aligned with their expectations and requirements.

We offer the following services in this area:

  • Strategic publication planning
  • Manuscripts
  • Abstract development and submission
  • Poster design and layout
  • KOL liaison and management
  • Congress support

We recognise the importance of the authors’ contributions to a publication, and indeed what marks us out is our ability to earn the long-term respect of KOLs through our command of the science. We handle the whole publication process, including strategic guidance, literature searching, reviews of competitor data display, publication submission and peer review. We are capable of extracting data directly from clinical trial tables, figures and listings, without simply reproducing text from clinical study reports, and we always perform an extensive and thorough quality control procedure to ensure complete accuracy of the data reported, as well as alignment with all relevant publications guidelines. We believe that we offer excellent value to our clients, with fees agreed at the start of the project and no hidden costs, regardless of the number of review cycles and revisions required.

Please contact Jeanette Kusel for further information about our publications services.

We were asked by a client to produce three manuscripts, presenting the primary data from two clinical trials in separate indications, for concurrent submission and publication in a high impact factor journal. We were required to manage the full process, including initiation, literature searching, writing, review management, submission, and peer-review processes.

The manuscripts were based on data taken directly from the clinical trial tables, figures and listings, and required a substantial degree of interpretation and scientific understanding. We devoted a stable project team to all three manuscripts, and provided the client and authors with multiple drafts plus an initial outline and final approval versions.

There were several challenges associated with the development of these publications. In one manuscript, there was considerable disagreement regarding the nomenclature used to describe certain disease aspects, and we were required to interact directly with different KOLs to assist in negotiating language which was acceptable to all authors. Additionally, the client provided a number of post-hoc analyses, which were requested for inclusion at short notice, requiring us to quickly assimilate the new information and include it in subsequent drafts. To ensure concurrent publication of the three manuscripts in the same journal issue, we addressed substantial peer-review comments for one manuscript in under three weeks, and reviewed the final proofs in under two days.

Our fast turnaround times and careful planning enabled us to deliver all three manuscripts to our own stringent quality standards with a high degree of consistency across publications, and it was especially rewarding for all involved to see the three articles published simultaneously in the journal targeted by the client and authors.

A client requested that we develop a substantial number of abstracts (32 in total) for submission to an international medical research congress attended by leading scientists and physicians. The abstracts reported numerous types of data (including clinical and pre-clinical data, post-hoc efficacy analyses, safety data and modelling analyses) for two separate drugs across multiple disease areas. These data were based on a range of information sources including tables, figures and listings from primary studies, as well as clinical study reports.

We devoted a substantial amount of resource to the project, working in close collaboration with the client and external authors, and were responsible for multiple project aspects including compliance processes, scientific writing, review management and website submission. Our work on this project resulted in a very high abstract acceptance rate: 30 abstracts were accepted by the congress for publication, including 25 poster presentations and 2 podium presentations.

Following the notifications, we had approximately 2 months to develop these presentations. This involved development of all scientific content from the outline stage to final versions, in addition to requesting and inserting additional data and figures, managing multiple parallel review stages and implementing the final quality control checks.

During the development of these publications we identified data gaps which could strengthen and improve the publications. This meant that we had to liaise directly with the study statisticians in order to initiate further analyses. Another challenge that we faced was managing conflicting comments from different reviewers and authors, which required us to produce a balanced presentation of the data upon which all could agree.

The posters themselves were produced by our in-house Graphic Design Team, who developed poster templates using specialist design software, managed the full design and layout of posters, and organised the printing and shipping processes. Working internally with our in-house designers enabled us to provide a rapid turnaround of review comments, as well as allowing clients and authors to contribute directly to the design and posters.

As part of this project, we also suggested and developed an iPad application which could be used by the client team on-site at the congress to inform and educate their team about their publications at that congress. As with the posters themselves, this iPad tool was very well-received by the team.

At the request of the client, we also provided on-site support at the congress itself, managing the final delivery of presentation materials, organising mounting and removal of posters at the appropriate times, and coordinating presenter availability, which involved contacting KOLs to determine the times at which they were available to present and arranging cover where necessary.